Antagonism at receptors other than d2 and 5ht2 see pharmacokinetics may explain some of the other effects of risperdal.

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Increased mortality in elderly patients with dementia-related psychosis [see BOXED WARNING and WARNINGS AND PRECAUTIONS ] Cerebrovascular adverse events.including elderly patients with dementia-related psychosis [see WARNINGS AND PRECAUTIONS ] Neuroleptic malignant syndrome [see WARNINGS AND PRECAUTIONS ] Tardive dyskinesia [see WARNINGS AND PRECAUTIONS ] Metabolic Changes (Hyperglycemia and diabetes mellitus.Dyslipidemia.and Weight Gain) [seeWARNINGS AND PRECAUTIONS ] Hyperprolactinemia [see WARNINGS AND PRECAUTIONS ] Orthostatic hypotension [see WARNINGS AND PRECAUTIONS ] Leukopenia.neutropenia.and agranulocytosis [see WARNINGS AND PRECAUTIONS ] Potential for cognitive and motor impairment [see WARNINGS AND PRECAUTIONS ] Seizures [see WARNINGS AND PRECAUTIONS ] Dysphagia [see WARNINGS AND PRECAUTIONS ] Priapism [see WARNINGS AND PRECAUTIONS ] Disruption of body temperature regulation [see WARNINGS AND PRECAUTIONS ] Patients with Phenylketonuria [see WARNINGS AND PRECAUTIONS ].

Drug-drug. Antihistamines.opioids.sedative-hypnotics. additive CNS depression.

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Risperidone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness.fainting) that need medical attention right away.

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